Wet Lab Research: Interdisciplinary Drug Discovery and Repurposing for Hearing Loss Prevention and Treatment.
We have developed novel computational approaches that leverage big data (clinical, gene expression, pharmacological, and molecular data) for high-throughput drug screening and repurposing. Combined with unbiased animal models and clinical trials, our state-of-the-art methods significantly improves drug screening efficiency, preclinical-to-clinical translatability, and as a result the likelihood of successful drug development programs. Our drug discovery pipeline is creating novel therapeutics that will prevent or restore hearing loss that affects 15% Americans and 500 million people worldwide.